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Image Search Results
Journal: Frontiers in Oncology
Article Title: A tumor cell specific Zona Pellucida glycoprotein 3 RNA transcript encodes an intracellular cancer antigen
doi: 10.3389/fonc.2023.1233039
Figure Lengend Snippet: ZP3-Cancer is the dominant transcript in tumor cells and is differentially distributed among cancer types. (A) Expression of the seven annotated ZP3 transcripts in CCls (n=1339). Bars represent Tukey box plots (boxes are median+IQR). Median transcript expression levels (from left to right) are 2.47, 0.22, 0.0, 0.04, 0.42, 0.0 and 0.0 TPM. ZP3-Cancer expression is significantly higher compared to all other transcripts (Kruskal-Wallis test, p < 0.0001). NC = Non-protein coding. (B) Relative expression of ZP3-cancer and ZP3-Oocyte in the CCLs MCF7 and HeLa, and in healthy ovarian tissue containing follicles, as determined by qPCR. ZP3-Cancer expression is set to 1 for MCF7 and HeLa, ZP3-Oocyte expression is set to 1 for ovarian tissue. ‘ZP3-both’ served as a positive control and used primers designed to detect ZP3-Cancer and ZP3-Oocyte simultaneously. Bars represent mean+SD for the triplicate qPCR reactions. (C) Differential expression of ZP3-Cancer in the cancer types covered by the CCLs. Cancer types represented by less than 5 CCLs were not included. Bars represent Tukey box plots (boxes are median+IQR). Number of samples are indicated between brackets. The shaded area indicates CCLs with a ZP3-Cancer expression level below the overall median (2.54 TPM).
Article Snippet: Total RNA extracted from the
Techniques: Expressing, Positive Control
Journal: BMC Cancer
Article Title: Aberrant methylation of the M-type phospholipase A 2 receptor gene in leukemic cells
doi: 10.1186/1471-2407-12-576
Figure Lengend Snippet: PLA2R1 gene methylations in different human cell lines
Article Snippet: In addition, genomic DNA from Raji (human B-cell leukemia),
Techniques: Methylation
Journal: Asian Pacific Journal of Cancer Prevention : APJCP
Article Title: Unexpected Lower Expression of Oncoprotein Gankyrin in Drug Resistant ABCG2 Overexpressing Breast Cancer Cell Lines
doi: 10.22034/APJCP.2017.18.12.3413
Figure Lengend Snippet: The Expression of ABCG2 at mRNA Level in MCF-7 Derived Breast Cancer Cell Lines. ABCG2 mRNA level is compared between drug resistance cell line MCF-7/MX and its parental non-resistance MCF-7 cells. Real-time RT-PCR analysis was performed on total RNA extracted from cells. Values were normalized to the β-actin content of samples and expressed as mean ±SEM (n = 3). Statistical significance was calculated by one-way Analysis of variance (ANOVA) and Tukey’s post-hoc; ***p < 0.001 compared with the non-resistance parental cell line.
Article Snippet:
Techniques: Expressing, Derivative Assay, Quantitative RT-PCR